Activity of ADAM17 (a Disintegrin and Metalloprotease 17) Is Regulated by Its Noncatalytic Domains and Secondary Structure of its Substrates

Por Stawikowska, Roma, Cudic, Mare, Giulianotti, Marc, Houghten, Richard A., Fields, Gregg B., Minond, Dmitriy
Publicado em 2013

Glycosylation of A Disintegrin And Metalloprotease 17 (ADAM17) Affects its Activity and Inhibition

Por Chavaroche, Anais, Cudic, Mare, Giulianotti, Marc, Houghten, Richard A., Fields, Gregg B., Minond, Dmitriy
Publicado no Anal Biochem (2013)

COPS5 (Jab1) Protein Increases β Site Processing of Amyloid Precursor Protein and Amyloid β Peptide Generation by Stabilizing RanBP9 Protein Levels

Por Wang, Hongjie, Dey, Debleena, Carrera, Ivan, Minond, Dmitriy, Bianchi, Elisabetta, Xu, Shaohua, Lakshmana, Madepalli K.
Publicado em 2013

Discovery of Novel Inhibitors of a Disintegrin and Metalloprotease 17 (ADAM17) Using Glycosylated and Non-glycosylated Substrates

Por Minond, Dmitriy, Cudic, Mare, Bionda, Nina, Giulianotti, Marc, Maida, Laura, Houghten, Richard A., Fields, Gregg B.
Publicado em 2012

Identification of Specific Hemopexin-like Domain Residues That Facilitate Matrix Metalloproteinase Collagenolytic Activity

Por Lauer-Fields, Janelle L., Chalmers, Michael J., Busby, Scott A., Minond, Dmitriy, Griffin, Patrick R., Fields, Gregg B.
Publicado em 2009

Identification of Novel, Exosite-Binding Matrix Metalloproteinase-13 Inhibitor Scaffolds

Por Roth, Joshua, Minond, Dmitriy, Darout, Etzer, Liu, Qin, Lauer, Janelle, Hodder, Peter, Fields, Gregg B., Roush, William R.
Publicado em 2011

High throughput screening of potentially selective MMP-13 exosite inhibitors utilizing a triple-helical FRET substrate

Por Lauer-Fields, Janelle L., Minond, Dmitriy, Chase, Peter S., Baillargeon, Pierre E., Saldanha, S. Adrian, Stawikowska, Roma, Hodder, Peter, Fields, Gregg B.
Publicado em 2008

Differentiation of Secreted and Membrane-Type Matrix Metalloproteinase Activities Based on Substitutions and Interruptions of Triple-Helical Sequences

Por Minond, Dmitriy, Lauer-Fields, Janelle L., Cudic, Mare, Overall, Christopher M., Pei, Duanqing, Brew, Keith, Moss, Marcia L., Fields, Gregg B.
Publicado em 2007

Development of HTS Assays and Pilot Screen for Inhibitors of Metalloproteases Meprin α and β

Por Madoux, Franck, Tredup, Claudia, Spicer, Timothy P., Scampavia, Louis, Chase, Peter S., Hodder, Peter S., Fields, Gregg B., Becker-Pauly, Christoph, Minond, Dmitriy
Publicado no Biopolymers (2014)

Novel Pyrrolidine Diketopiperazines Selectively Inhibit Melanoma Cells via Induction of Late-Onset Apoptosis

Por Onwuha-Ekpete, Lillian, Tack, Lisa, Knapinska, Anna, Smith, Lyndsay, Kaushik, Gaurav, LaVoi, Travis, Giulianotti, Marc, Houghten, Richard A., Fields, Gregg B., Minond, Dmitriy
Publicado em 2014

Characterization of Selective Exosite-Binding Inhibitors of Matrix Metalloproteinase 13 That Prevent Articular Cartilage Degradation in Vitro

Por Spicer, Timothy P., Jiang, Jianwen, Taylor, Alexander B., Choi, Jun Yong, Hart, P. John, Roush, William R., Fields, Gregg B., Hodder, Peter S., Minond, Dmitriy
Publicado no J Med Chem (2014)

Inhibitors of VIM-2 by Screening Pharmacogically Active and Click-Chemistry Compound Libraries

Por Minond, Dmitriy, Saldanha, S. Adrian, Subramaniam, Prem, Spaargaren, Michael, Spicer, Timothy, Fotsing, Joseph R., Weide, Timo, Fokin, Valery, Sharpless, Barry, Galleni, Moreno, Frère, Jean-Marie, Hodder, Peter
Publicado em 2009

NH-1,2,3-Triazole Inhibitors of the VIM-2 Metallo-β-Lactamase

Por Weide, Timo, Saldanha, S. Adrian, Minond, Dmitriy, Spicer, Timothy P., Fotsing, Joseph R., Spaargaren, Michael, Frère, Jean-Marie, Bebrone, Carine, Sharpless, K. Barry, Hodder, Peter S., Fokin, Valery V.
Publicado em 2010

Hydroxyquinoline-derived compounds and analoguing of selective MCL-1 inhibitors using a functional biomarker

Por Richard, David J., Lena, Ryan, Bannister, Thomas, Blake, Noel, Pierceall, William E., Carlson, Nicole E., Keller, Christina Eberhart, Koenig, Marcel, He, Yuanjun, Minond, Dmitriy, Mishra, Jitendra, Cameron, Michael, Spicer, Timothy, Hodder, Peter, Cardone, Michael H.
Publicado em 2013

Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

Por Chou, Tsui-Fen, Brown, Steve J., Minond, Dmitriy, Nordin, Brian E., Li, Kelin, Jones, Amanda C., Chase, Peter, Porubsky, Patrick R., Stoltz, Brian M., Schoenen, Frank J., Patricelli, Matthew P., Hodder, Peter, Rosen, Hugh, Deshaies, Raymond J.
Publicado em 2011