NH-1,2,3-Triazole Inhibitors of the VIM-2 Metallo-β-Lactamase

[Image: see text] Metallo-β-lactamases (MBLs) are an emerging cause of bacterial resistance to antibiotic treatment. The VIM-2 β-lactamase is the most commonly encountered MBLs in clinical isolates worldwide. Described here are potent and selective small molecule inhibitors of VIM-2 containing the a...

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Bibliografiske detaljer
Main Authors: Weide, Timo, Saldanha, S. Adrian, Minond, Dmitriy, Spicer, Timothy P., Fotsing, Joseph R., Spaargaren, Michael, Frère, Jean-Marie, Bebrone, Carine, Sharpless, K. Barry, Hodder, Peter S., Fokin, Valery V.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2010
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901175/
https://ncbi.nlm.nih.gov/pubmed/20625539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml900022q
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