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Inhibitors of VIM-2 by Screening Pharmacogically Active and Click-Chemistry Compound Libraries

VIM-2 is an Ambler class B metallo-β-lactamase (MBL) capable of hydrolyzing a broad-spectrum of β-lactam antibiotics. Although the discovery and development of MBL inhibitors continues to be an area of active research, an array of potent, small molecule inhibitors has yet to be fully characterized f...

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書誌詳細
主要な著者: Minond, Dmitriy, Saldanha, S. Adrian, Subramaniam, Prem, Spaargaren, Michael, Spicer, Timothy, Fotsing, Joseph R., Weide, Timo, Fokin, Valery, Sharpless, Barry, Galleni, Moreno, Frère, Jean-Marie, Hodder, Peter
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759276/
https://ncbi.nlm.nih.gov/pubmed/19553129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.05.070
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