Llwytho...

Identification of Novel, Exosite-Binding Matrix Metalloproteinase-13 Inhibitor Scaffolds

Matrix metalloproteinase 13 (MMP-13) has been implicated as the protease responsible for collagen degradation in cartilage during osteoarthritis (OA). Compounds that inhibit the metalloproteinase at the Zn binding site typically lack specificity among MMP family members. Analogs of the low-micromola...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Roth, Joshua, Minond, Dmitriy, Darout, Etzer, Liu, Qin, Lauer, Janelle, Hodder, Peter, Fields, Gregg B., Roush, William R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210410/
https://ncbi.nlm.nih.gov/pubmed/22018790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.09.077
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!