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Exosite Interactions Impact Matrix Metalloproteinase Collagen Specificities

Members of the matrix metalloproteinase (MMP) family selectively cleave collagens in vivo. However, the substrate structural determinants that facilitate interaction with specific MMPs are not well defined. We hypothesized that type I–III collagen sequences located N- or C-terminal to the physiologi...

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Detalhes bibliográficos
Main Authors: Robichaud, Trista K., Steffensen, Bjorn, Fields, Gregg B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199499/
https://ncbi.nlm.nih.gov/pubmed/21896477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.273391
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