The Role of Collagen Charge Clusters in the Modulation of Matrix Metalloproteinase Activity

Members of the matrix metalloproteinase (MMP) family selectively cleave collagens in vivo. Several substrate structural features that direct MMP collagenolysis have been identified. The present study evaluated the role of charged residue clusters in the regulation of MMP collagenolysis. A series of...

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Bibliografske podrobnosti
Main Authors: Lauer, Janelle L., Bhowmick, Manishabrata, Tokmina-Roszyk, Dorota, Lin, Yan, Van Doren, Steven R., Fields, Gregg B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Enzymology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900948/
https://ncbi.nlm.nih.gov/pubmed/24297171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.513408
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