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Peptide-Based Selective Inhibitors of Matrix Metalloproteinase-Mediated Activities

The matrix metalloproteinases (MMPs) exhibit a broad array of activities, some catalytic and some non-catalytic in nature. An overall lack of selectivity has rendered small molecule, active site targeted MMP inhibitors problematic in execution. Inhibitors that favor few or individual members of the...

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Détails bibliographiques
Auteurs principaux: Ndinguri, Margaret W., Bhowmick, Manishabrata, Tokmina-Roszyk, Dorota, Robichaud, Trista K., Fields, Gregg B.
Format: Artigo
Langue:Inglês
Publié: MDPI 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678729/
https://ncbi.nlm.nih.gov/pubmed/23201642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules171214230
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