Second Generation Triple-Helical Peptide Inhibitors of Matrix Metalloproteinases

The design of selective matrix metalloproteinase (MMP) inhibitors that also possess favorable solubility properties has proved to be especially challenging. A prior approach using collagen-model templates combined with transition state analogs produced a first generation of triple-helical peptide in...

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Vydáno v:J Med Chem
Hlavní autoři: Bhowmick, Manishabrata, Tokmina-Roszyk, Dorota, Onwuha-Ekpete, Lillian, Harmon, Kelli, Robichaud, Trista, Fuerst, Rita, Stawikowska, Roma, Steffensen, Bjorn, Roush, William, Wong, Hector R., Fields, Gregg B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413923/
https://ncbi.nlm.nih.gov/pubmed/28394608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.7b00018
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