Matrix Metalloproteinase Inhibition by Heterotrimeric Triple-Helical Peptide Transition State Analogs

Matrix metalloproteinases (MMPs) have been implicated in numerous pathologies. An overall lack of selectivity has rendered active site targeted MMP inhibitors problematic. The present study describes MMP inhibitors that function by binding both secondary binding sites (exosites) and the active site....

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Detaylı Bibliyografya
Yayımlandı:Chembiochem
Asıl Yazarlar: Bhowmick, Manishabrata, Stawikowska, Roma, Tokmina-Roszyk, Dorota, Fields, Gregg B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415627/
https://ncbi.nlm.nih.gov/pubmed/25766890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402716
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