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Triple-Helical Transition State Analogs: A New Class of Selective Matrix Metalloproteinase Inhibitors
Alterations in activities of one family of proteases, the matrix metalloproteinases (MMPs), have been implicated in primary and metastatic tumor growth, angiogenesis, and pathological degradation of extracellular matrix (ECM) components, such as collagen and laminin. Since hydrolysis of the collagen...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2531068/ https://ncbi.nlm.nih.gov/pubmed/17672455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0715849 |
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