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Matrix Metalloproteinase Triple-Helical Peptide Inhibitors: Potential Cross-Reactivity with Caspase-11

Triple-helical peptide inhibitors (THPIs) of matrix metalloproteinases (MMPs) have recently been demonstrated to be effective in a variety of animal models of disease, coincidental with knockout studies. However, passenger mutations have been described in MMP knockout mice that impact the activity o...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Knapinska, Anna M., Hart, Melissa, Drotleff, Gary, Fields, Gregg B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930605/
https://ncbi.nlm.nih.gov/pubmed/31795279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24234355
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