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Matrix Metalloproteinase 13 Inhibitors for Modulation of Osteoclastogenesis: Enhancement of Solubility and Stability

Matrix metalloproteinase 13 (MMP-13) activity has been correlated to breast cancer bone metastasis. It has been proposed that MMP-13 contributes to bone metastasis via promotion of osteoclastogeneis. To explore the mechanisms of MMP-13 action, we previously described a highly efficacious and selecti...

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Bibliografiske detaljer
Udgivet i:ChemMedChem
Main Authors: Knapinska, Anna M., Singh, Chandani, Drotleff, Gary, Blanco, Daniela, Chai, Cedric, Schwab, Jason, Herd, Anu, Fields, Gregg B.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035250/
https://ncbi.nlm.nih.gov/pubmed/33331147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000911
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