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Selective Modulation of Matrix Metalloproteinase 9 (MMP-9) Functions via Exosite Inhibition
Unregulated activities of the matrix metalloproteinase (MMP) family have been implicated in primary and metastatic tumor growth, angiogenesis, and pathological degradation of extracellular matrix components, such as collagen and laminin. However, clinical trials with small molecule MMP inhibitors ha...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2459303/ https://ncbi.nlm.nih.gov/pubmed/18499673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801438200 |
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