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Selective Modulation of Matrix Metalloproteinase 9 (MMP-9) Functions via Exosite Inhibition

Unregulated activities of the matrix metalloproteinase (MMP) family have been implicated in primary and metastatic tumor growth, angiogenesis, and pathological degradation of extracellular matrix components, such as collagen and laminin. However, clinical trials with small molecule MMP inhibitors ha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Lauer-Fields, Janelle L., Whitehead, John K., Li, Shunzi, Hammer, Robert P., Brew, Keith, Fields, Gregg B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2459303/
https://ncbi.nlm.nih.gov/pubmed/18499673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801438200
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