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Identification of Specific Hemopexin-like Domain Residues That Facilitate Matrix Metalloproteinase Collagenolytic Activity

Collagen serves as a structural scaffold and a barrier between tissues, and thus collagen catabolism (collagenolysis) is required to be a tightly regulated process in normal physiology. In turn, the destruction or damage of collagen during pathological states plays a role in tumor growth and invasio...

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Autori principali: Lauer-Fields, Janelle L., Chalmers, Michael J., Busby, Scott A., Minond, Dmitriy, Griffin, Patrick R., Fields, Gregg B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781996/
https://ncbi.nlm.nih.gov/pubmed/19574232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.016873
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