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Development of HTS Assays and Pilot Screen for Inhibitors of Metalloproteases Meprin α and β
Zinc metalloproteinases meprin α and meprin β are implicated in a variety of diseases, such as fibrosis, inflammation and neurodegeneration, however, there are no selective small molecule inhibitors that would allow to study their role in these processes. To address this lack of molecular tools we h...
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| Veröffentlicht in: | Biopolymers |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4339026/ https://ncbi.nlm.nih.gov/pubmed/25048711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22527 |
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