Reversal of Neuronal Migration in a Mouse Model of Fetal Alcohol Syndrome by Controlling Second-Messenger Signalings

Por Kumada, Tatsuro, Lakshmana, Madepalli K., Komuro, Hitoshi
Publicado no J Neurosci (2006)

RanBP9 Overexpression Accelerates Loss of Pre and Postsynaptic Proteins in the APΔE9 Transgenic Mouse Brain

Por Wang, Hongjie, Wang, Ruizhi, Xu, Shaohua, Lakshmana, Madepalli K.
Publicado em 2014

Substituted dithiazole piperazine benzamides as novel amyloid beta peptide reducing agents

Por Wang, Hongjie, Wang, Ruizhi, Lakshmana, Madepalli K, Nefzi, Adel
Publicado no Bioorg Med Chem Lett (2014)

Transcription Factor EB Is Selectively Reduced in the Nuclear Fractions of Alzheimer's and Amyotrophic Lateral Sclerosis Brains

Por Wang, Hongjie, Wang, Ruizhi, Xu, Shaohua, Lakshmana, Madepalli K.
Publicado no Neurosci J (2016)

Correction: RanBP9 Overexpression Accelerates Loss of Pre and Postsynaptic Proteins in the APΔE9 Transgenic Mouse Brain

Por Wang, Hongjie, Wang, Ruizhi, Xu, Shaohua, Lakshmana, Madepalli K.
Publicado no PLoS One (2019)

C-terminal 37 residues of LRP promote the amyloidogenic processing of APP independent of FE65

Por Lakshmana, Madepalli K, Chen, Eunice, Yoon, Il-Sang, Kang, David E
Publicado em 2008

RanBP9 overexpression reduces dendritic arbor and spine density

Por Wang, Hongjie, Lewsadder, Meagan, Dorn, Eric, Xu, Shaohua, Lakshmana, Madepalli K.
Publicado em 2014

COPS5 Protein Overexpression Increases Amyloid Plaque Burden, Decreases Spinophilin-immunoreactive Puncta, and Exacerbates Learning and Memory Deficits in the Mouse Brain

Por Wang, Ruizhi, Wang, Hongjie, Carrera, Ivan, Xu, Shaohua, Lakshmana, Madepalli K.
Publicado no J Biol Chem (2015)

TFEB Overexpression in the P301S Model of Tauopathy Mitigates Increased PHF1 Levels and Lipofuscin Puncta and Rescues Memory Deficits12

Por Wang, Hongjie, Wang, Ruizhi, Carrera, Ivan, Xu, Shaohua, Lakshmana, Madepalli K.
Publicado no eNeuro (2016)

Pivotal role of RanBP9 in integrin-dependent focal adhesion signaling and assembly

Por Woo, Jung A., Roh, Seung-Eon, Lakshmana, Madepalli K., Kang, David E.
Publicado em 2012

Chronic Cladribine Administration Increases Amyloid Beta Peptide Generation and Plaque Burden in Mice

Por Hayes, Crystal D., Dey, Debleena, Palavicini, Juan Pablo, Wang, Hongjie, Araki, Wataru, Lakshmana, Madepalli K.
Publicado em 2012

COPS5 (Jab1) Protein Increases β Site Processing of Amyloid Precursor Protein and Amyloid β Peptide Generation by Stabilizing RanBP9 Protein Levels

Por Wang, Hongjie, Dey, Debleena, Carrera, Ivan, Minond, Dmitriy, Bianchi, Elisabetta, Xu, Shaohua, Lakshmana, Madepalli K.
Publicado em 2013

The neurotoxicity of amyloid β-protein oligomers is reversible in a primary neuron model

Por Tanokashira, Daisuke, Mamada, Naomi, Yamamoto, Fumiko, Taniguchi, Kaori, Tamaoka, Akira, Lakshmana, Madepalli K., Araki, Wataru
Publicado no Mol Brain (2017)

Novel Role of RanBP9 in BACE1 Processing of Amyloid Precursor Protein and Amyloid β Peptide Generation

Por Lakshmana, Madepalli K., Yoon, Il-Sang, Chen, Eunice, Bianchi, Elizabetta, Koo, Edward H., Kang, David E.
Publicado em 2009

A fragment of the scaffolding protein RanBP9 is increased in Alzheimer’s disease brains and strongly potentiates amyloid-β peptide generation

Por Lakshmana, Madepalli K., Chung, John Y., Wickramarachchi, Supul, Tak, Eileen, Bianchi, Elisabetta, Koo, Edward H., Kang, David E.
Publicado em 2010

LRP1 Downregulates the Alzheimer’s β-Secretase BACE1 by Modulating Its Intraneuronal Trafficking1,2,3

Por Tanokashira, Daisuke, Motoki, Kazumi, Minegishi, Seiji, Hosaka, Ai, Mamada, Naomi, Tamaoka, Akira, Okada, Takashi, Lakshmana, Madepalli K., Araki, Wataru
Publicado no eNeuro (2015)

Role of RanBP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain

Por Lakshmana, Madepalli K., Hayes, Crystal D., Bennett, Steven P., Bianchi, Elisabetta, Reddy, Konda M., Koo, Edward H., Kang, David E.
Publicado em 2012

Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustine

Por Hayes, Crystal D, Dey, Debleena, Palavicini, Juan Pablo, Wang, Hongjie, Patkar, Kshitij A, Minond, Dimitriy, Nefzi, Adel, Lakshmana, Madepalli K
Publicado em 2013

RanBP9 Plays a Critical Role in Neonatal Brain Development in Mice

Por Palavicini, Juan Pablo, Lloyd, Brandon Noel, Hayes, Crystal D., Bianchi, Elisabetta, Kang, David E., Dawson-Scully, Ken, Lakshmana, Madepalli K.
Publicado em 2013

RanBP9 Overexpression Accelerates Loss of Dendritic Spines in a Mouse Model of Alzheimer's Disease

Por Wang, Ruizhi, Palavicini, Juan Pablo, Wang, Hongjie, Maiti, Panchanan, Bianchi, Elisabetta, Xu, Shaohua, Lloyd, BN, Dawson-Scully, Ken, Kang, David E, Lakshmana, Madepalli K.
Publicado em 2014