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Substituted dithiazole piperazine benzamides as novel amyloid beta peptide reducing agents

Alzheimer’s disease is a persistent neurodegenerative disorder of elderly characterized clinically by irreversible loss of memory due to accumulation of amyloid beta peptides within the amyloid plaques. We report the parallel synthesis and screening results of diverse substituted di-thiazole piperaz...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Wang, Hongjie, Wang, Ruizhi, Lakshmana, Madepalli K, Nefzi, Adel
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311522/
https://ncbi.nlm.nih.gov/pubmed/25155386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.08.022
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