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Pivotal role of RanBP9 in integrin-dependent focal adhesion signaling and assembly

Accumulation of the amyloid β (Aβ) peptide derived from the amyloid precursor protein (APP) plays a central role in the pathogenesis of Alzheimer's disease (AD). We previously reported that the scaffolding protein RanBP9 is markedly increased in AD brains and promotes Aβ generation by scaffoldi...

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Main Authors: Woo, Jung A., Roh, Seung-Eon, Lakshmana, Madepalli K., Kang, David E.
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316903/
https://ncbi.nlm.nih.gov/pubmed/22223749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-194423
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