Pharmacological Characterization of GPR55, A Putative Cannabinoid Receptor

Por Sharir, Haleli, Abood, Mary E.
Publicado em 2010

Zinc Released from Injured Cells Is Acting via the Zn(2+)-sensing Receptor, ZnR, to Trigger Signaling Leading to Epithelial Repair

Por Sharir, Haleli, Zinger, Anna, Nevo, Andrey, Sekler, Israel, Hershfinkel, Michal
Publicado em 2010

Activation of GPR18 by cannabinoid compounds: a tale of biased agonism

Por Console-Bram, Linda, Brailoiu, Eugen, Brailoiu, Gabriela Cristina, Sharir, Haleli, Abood, Mary E
Publicado em 2014

The endocannabinoids anandamide and virodhamine modulate the activity of the candidate cannabinoid receptor GPR55

Por Sharir, Haleli, Console-Bram, Linda, Mundy, Christina, Popoff, Steven N., Kapur, Ankur, Abood, Mary E
Publicado em 2012

Atypical Responsiveness of the Orphan Receptor GPR55 to Cannabinoid Ligands

Por Kapur, Ankur, Zhao, Pingwei, Sharir, Haleli, Bai, Yushi, Caron, Marc G., Barak, Larry S., Abood, Mary E.
Publicado em 2009

Identification of crucial amino acid residues involved in agonist signaling at the GPR55 receptor

Por Lingerfelt, Mary A., Zhao, Pingwei, Sharir, Haleli P., Hurst, Dow P., Reggio, Patricia H., Abood, Mary E.
Publicado no Biochemistry (2017)

Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments

Por Snitser, Olga, Russ, Dor, Stone, Laura K., Wang, Kathy K., Sharir, Haleli, Kozer, Noga, Cohen, Galit, Barr, Haim M., Kishony, Roy
Publicado no Nat Commun (2020)

A Pharmacochaperone-Based High-Throughput Screening Assay for the Discovery of Chemical Probes of Orphan Receptors

Por Morfa, Camilo J., Bassoni, Daniel, Szabo, Andras, McAnally, Danielle, Sharir, Haleli, Hood, Becky L., Vasile, Stefan, Wehrman, Tom, Lamerdin, Jane, Smith, Layton H.
Publicado no Assay Drug Dev Technol (2018)

CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides

Por Lucchesi, Valentina, Hurst, Dow P., Shore, Derek M., Bertini, Simone, Ehrmann, Brandie M., Allarà, Marco, Lawrence, Lyle, Ligresti, Alessia, Minutolo, Filippo, Saccomanni, Giuseppe, Sharir, Haleli, Macchia, Marco, Di Marzo, Vincenzo, Abood, Mary E., Reggio, Patricia H., Manera, Clementina
Publicado no J Med Chem (2014)

IDENTIFICATION OF THE GPR55 AGONIST BINDING SITE USING A NOVEL SET OF HIGH POTENCY GPR55 SELECTIVE LIGANDS

Por Kotsikorou, Evangelia, Madrigal, Karla E., Hurst, Dow P., Sharir, Haleli, Lynch, Diane L., Heynen-Genel, Susanne, Milan, Loribelle B., Chung, Thomas D.Y., Seltzman, Herbert H., Bai, Yushi, Caron, Marc G., Barak, Larry, Abood, Mary E., Reggio, Patricia H.
Publicado em 2011

Targeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptiv...

Por Zhao, Pingwei, Sharir, Haleli, Kapur, Ankur, Cowan, Alan, Geller, Ellen B., Adler, Martin W., Seltzman, Herbert H., Reggio, Patricia H., Heynen-Genel, Susanne, Sauer, Michelle, Chung, Thomas D.Y., Bai, Yushi, Chen, Wei, Caron, Marc G., Barak, Larry S., Abood, Mary E.
Publicado em 2010

Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones

Por Meza-Aviña, Maria Elena, Lingerfelt, Mary A., Console-Bram, Linda M., Gamage, Thomas F., Sharir, Haleli, Gettys, Kristen E., Hurst, Dow P., Kotsikorou, Evangelia, Shore, Derek M., Caron, Marc G., Rao, Narasinga, Barak, Larry S., Abood, Mary E., Reggio, Patricia H., Croatt, Mitchell P.
Publicado no Bioorg Med Chem Lett (2016)

IDENTIFICATION OF THE GPR55 ANTAGONIST BINDING SITE USING A NOVEL SET OF HIGH POTENCY GPR55 SELECTIVE LIGANDS

Por Kotsikorou, Evangelia, Sharir, Haleli, Shore, Derek M., Hurst, Dow P., Lynch, Diane L., Madrigal, Karla E., Heynen-Genel, Susanne, Milan, Loribelle B., Chung, Thomas D.Y., Seltzman, Herbert H., Bai, Yushi, Caron, Marc G., Barak, Larry S., Croatt, Mitchell P., Abood, Mary E., Reggio, Patricia H.
Publicado em 2013