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Identification of crucial amino acid residues involved in agonist signaling at the GPR55 receptor
GPR55 is a newly de-orphanized Class A GPCR that has been implicated in inflammatory pain, neuropathic pain, metabolic disorder, bone development, and cancer. Few potent GPR55 ligands have been identified to date. This is largely due to an absence of information about salient features of GPR55, such...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338039/ https://ncbi.nlm.nih.gov/pubmed/28005346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01013 |
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