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Identification of crucial amino acid residues involved in agonist signaling at the GPR55 receptor

GPR55 is a newly de-orphanized Class A GPCR that has been implicated in inflammatory pain, neuropathic pain, metabolic disorder, bone development, and cancer. Few potent GPR55 ligands have been identified to date. This is largely due to an absence of information about salient features of GPR55, such...

詳細記述

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書誌詳細
出版年:Biochemistry
主要な著者: Lingerfelt, Mary A., Zhao, Pingwei, Sharir, Haleli P., Hurst, Dow P., Reggio, Patricia H., Abood, Mary E.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338039/
https://ncbi.nlm.nih.gov/pubmed/28005346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01013
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