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Activation of GPR18 by cannabinoid compounds: a tale of biased agonism

BACKGROUND AND PURPOSE: GPR18 is a candidate cannabinoid receptor, but its classification as such is controversial. The rationale of the study presented herein was to consider the effects of N-arachidonoyl glycine (NAGly) and cannabinoids via differential G-protein coupled pathways, in addition to β...

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Detalhes bibliográficos
Main Authors: Console-Bram, Linda, Brailoiu, Eugen, Brailoiu, Gabriela Cristina, Sharir, Haleli, Abood, Mary E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128052/
https://ncbi.nlm.nih.gov/pubmed/24762058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12746
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