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Both HIV infected and uninfected cells express TRAILshort, which confers TRAIL resistance upon bystander cells within the microenvironment
Tumor necrosis factor related apoptosis-inducing ligand (TRAIL) was initially described to induce apoptosis of tumor cells and/or virally infected cells while sparing normal cells and has been implicated in the pathogenesis of HIV disease. We previously identified TRAILshort, a TRAIL splice variant,...
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Publicado no: | J Immunol |
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Main Authors: | , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5808399/ https://ncbi.nlm.nih.gov/pubmed/29263214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701113 |
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