Both HIV infected and uninfected cells express TRAILshort, which confers TRAIL resistance upon bystander cells within the microenvironment

Tumor necrosis factor related apoptosis-inducing ligand (TRAIL) was initially described to induce apoptosis of tumor cells and/or virally infected cells while sparing normal cells and has been implicated in the pathogenesis of HIV disease. We previously identified TRAILshort, a TRAIL splice variant,...

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Publicado en:J Immunol
Main Authors: Nie, Zilin, Aboulnasr, Fatma, Natesampillai, Sekar, Burke, Steve P., Krogman, Ashton, Bren, Gary D., Chung, Thomas D.Y., Anderson, Jeff R., Smart, Michele K., Katzmann, David J., Rajagopalan, Govindarajan, Cummins, Nathan W., Badley, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808399/
https://ncbi.nlm.nih.gov/pubmed/29263214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701113
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