Maintenance of the HIV Reservoir Is Antagonized by Selective BCL2 Inhibition

Decay of the HIV reservoir is slowed over time in part by expansion of the pool of HIV-infected cells. This expansion reflects homeostatic proliferation of infected cells by interleukin-7 (IL-7) or antigenic stimulation, as well as new rounds of infection of susceptible target cells. As novel therap...

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Bibliographic Details
Published in:J Virol
Main Authors: Cummins, Nathan W., Sainski-Nguyen, Amy M., Natesampillai, Sekar, Aboulnasr, Fatma, Kaufmann, Scott, Badley, Andrew D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432861/
https://ncbi.nlm.nih.gov/pubmed/28331083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00012-17
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