Reactivating latent HIV with PKC agonists induces resistance to apoptosis and is associated with phosphorylation and activation of BCL2

Eradication of HIV-1 by the “kick and kill” strategy requires reactivation of latent virus to cause death of infected cells by either HIV-induced or immune-mediated apoptosis. To date this strategy has been unsuccessful, possibly due to insufficient cell death in reactivated cells to effectively red...

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Библиографические подробности
Опубликовано в: :PLoS Pathog
Главные авторы: French, Andrea J., Natesampillai, Sekar, Krogman, Ashton, Correia, Cristina, Peterson, Kevin L., Alto, Alecia, Chandrasekar, Aswath P., Misra, Anisha, Li, Ying, Kaufmann, Scott H., Badley, Andrew D., Cummins, Nathan W.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2020
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595626/
https://ncbi.nlm.nih.gov/pubmed/33075109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008906
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