Integrins αvβ3 and α4β1 act as co-receptors for fractalkine and the integrin-binding defective mutant of fractalkine is an antagonist of CX3CR1

Por Fujita, Masaaki, Takada, Yoko K, Takada, Yoshikazu
Publicado em 2012

Insulin-like Growth Factor (IGF) Signaling Requires αvβ3-IGF1-IGF Type 1 Receptor (IGF1R) Ternary Complex Formation in Anchorage Independence, and the Complex Formation Does Not Re...

Por Fujita, Masaaki, Takada, Yoko K., Takada, Yoshikazu
Publicado em 2013

The Chemokine Fractalkine Can Activate Integrins without CX3CR1 through Direct Binding to a Ligand-Binding Site Distinct from the Classical RGD-Binding Site

Por Fujita, Masaaki, Takada, Yoko K., Takada, Yoshikazu
Publicado em 2014

Crosstalk between insulin-like growth factor (IGF) receptor and integrins through direct integrin binding to IGF1

Por Takada, Yoshikazu, Takada, Yoko K., Fujita, Masaaki
Publicado no Cytokine Growth Factor Rev (2017)

The Binding of Monomeric C-Reactive Protein (mCRP) to Integrins αvβ3 and α4β1 Is Related to Its Pro-Inflammatory Action

Por Fujita, Masaaki, Takada, Yoko K., Izumiya, Yoshihiro, Takada, Yoshikazu
Publicado em 2014

A Novel Fibroblast Growth Factor-1 (FGF1) Mutant that Acts as an FGF Antagonist

Por Yamaji, Satoshi, Saegusa, Jun, Ieguchi, Katsuaki, Fujita, Masaaki, Mori, Seiji, Takada, Yoko K., Takada, Yoshikazu
Publicado em 2010

Direct integrin binding to insulin-like growth factor-2 through the C-domain is required for insulin-like growth factor receptor type 1 (IGF1R) signaling

Por Cedano Prieto, Dora Maria, Cheng, Yushen, Chang, Chih-Chieh, Yu, Jessica, Takada, Yoko K., Takada, Yoshikazu
Publicado no PLoS One (2017)

Cross-talk between Integrin α6β4 and Insulin-like Growth Factor-1 Receptor (IGF1R) through Direct α6β4 Binding to IGF1 and Subsequent α6β4-IGF1-IGF1R Ternary Complex Formation in A...

Por Fujita, Masaaki, Ieguchi, Katsuaki, Davari, Parastoo, Yamaji, Satoshi, Taniguchi, Yukimasa, Sekiguchi, Kiyotoshi, Takada, Yoko K., Takada, Yoshikazu
Publicado em 2012

The Direct Binding of Insulin-like Growth Factor-1 (IGF-1) to Integrin αvβ3 Is Involved in IGF-1 Signaling

Por Saegusa, Jun, Yamaji, Satoshi, Ieguchi, Katsuaki, Wu, Chun-Yi, Lam, Kit S., Liu, Fu-Tong, Takada, Yoko K., Takada, Yoshikazu
Publicado em 2009

Direct Binding of the EGF-like Domain of Neuregulin-1 to Integrins (αvβ3 and α6β4) Is Involved in Neuregulin-1/ErbB Signaling

Por Ieguchi, Katsuaki, Fujita, Masaaki, Ma, Zi, Davari, Parastoo, Taniguchi, Yukimasa, Sekiguchi, Kiyotoshi, Wang, Bobby, Takada, Yoko K., Takada, Yoshikazu
Publicado em 2010

Proinflammatory Secreted Phospholipase A2 Type IIA (sPLA-IIA) Induces Integrin Activation through Direct Binding to a Newly Identified Binding Site (Site 2) in Integrins αvβ3, α4β1...

Por Fujita, Masaaki, Zhu, Kan, Fujita, Chitose K., Zhao, Min, Lam, Kit S., Kurth, Mark J., Takada, Yoko K., Takada, Yoshikazu
Publicado no J Biol Chem (2015)

Pro-inflammatory Secretory Phospholipase A2 Type IIA Binds to Integrins αvβ3 and α4β1 and Induces Proliferation of Monocytic Cells in an Integrin-dependent Manner

Por Saegusa, Jun, Akakura, Nobuaki, Wu, Chun-Yi, Hoogland, Case, Ma, Zi, Lam, Kit S., Liu, Fu-Tong, Takada, Yoko K., Takada, Yoshikazu
Publicado em 2008

A Dominant-Negative FGF1 Mutant (the R50E Mutant) Suppresses Tumorigenesis and Angiogenesis

Por Mori, Seiji, Tran, Vu, Nishikawa, Kyoko, Kaneda, Teruya, Hamada, Yoshinosuke, Kawaguchi, Naomasa, Fujita, Masaaki, Takada, Yoko K., Matsuura, Nariaki, Zhao, Min, Takada, Yoshikazu
Publicado em 2013

Direct Binding of Integrin αvβ3 to FGF1 Plays a Role in FGF1 Signaling

Por Mori, Seiji, Wu, Chun-Yi, Yamaji, Satoshi, Saegusa, Jun, Shi, Biao, Ma, Zi, Kuwabara, Yasuko, Lam, Kit S., Isseroff, R. Rivkah, Takada, Yoko K., Takada, Yoshikazu
Publicado em 2008

The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis

Por Mori, Seiji, Hatori, Nobuaki, Kawaguchi, Naomasa, Hamada, Yoshinosuke, Shih, Tsung-Chieh, Wu, Chun-Yi, Lam, Kit S., Matsuura, Nariaki, Yamamoto, Hirofumi, Takada, Yoko K., Takada, Yoshikazu
Publicado no Biosci Rep (2017)

Identification of Inhibitors against Interaction between Pro-inflammatory sPLA2-IIA Protein and Integrin αvβ3

Por Ye, Long, Dickerson, Tiffany, Kaur, Handeep, Takada, Yoko K., Fujita, Masaaki, Liu, Ruiwu, Knapp, John M., Lam, Kit S., Schore, Neil E., Kurth, Mark J., Takada, Yoshikazu
Publicado no Bioorg Med Chem Lett (2012)

A T cell-binding fragment of fibrinogen can prevent autoimmunity

Por Takada, Yoshikazu, Ono, Yoko, Saegusa, Jun, Mitsiades, Constantine, Mitsiades, Nicholas, Tsai, Jean, He, Yong, Maningding, Ernest, Coleman, Annie, Ramirez-Maverakis, Dalila, Rodriquez, Raphael, Takada, Yoko K., Maverakis, Emanual
Publicado em 2009

An Integrin Binding-defective Mutant of Insulin-like Growth Factor-1 (R36E/R37E IGF1) Acts as a Dominant-negative Antagonist of the IGF1 Receptor (IGF1R) and Suppresses Tumorigenes...

Por Fujita, Masaaki, Ieguchi, Katsuaki, Cedano-Prieto, Dora M., Fong, Andrew, Wilkerson, Charles, Chen, Jane Q., Wu, Mac, Lo, Su-Hao, Cheung, Anthony T. W., Wilson, Machelle D., Cardiff, Robert D., Borowsky, Alexander D., Takada, Yoko K., Takada, Yoshikazu
Publicado em 2013