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A Novel Fibroblast Growth Factor-1 (FGF1) Mutant that Acts as an FGF Antagonist
BACKGROUND: Crosstalk between integrins and FGF receptors has been implicated in FGF signaling, but the specifics of the crosstalk are unclear. We recently discovered that 1) FGF1 directly binds to integrin αvβ3, 2) the integrin-binding site and FGF receptor (FGFR) binding site are distinct, and 3)...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858075/ https://ncbi.nlm.nih.gov/pubmed/20422052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010273 |
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