A Dominant-Negative FGF1 Mutant (the R50E Mutant) Suppresses Tumorigenesis and Angiogenesis

Fibroblast growth factor-1 (FGF1) and FGF2 play a critical role in angiogenesis, a formation of new blood vessels from existing blood vessels. Integrins are critically involved in FGF signaling through crosstalk. We previously reported that FGF1 directly binds to integrin αvβ3 and induces FGF recept...

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Autori principali: Mori, Seiji, Tran, Vu, Nishikawa, Kyoko, Kaneda, Teruya, Hamada, Yoshinosuke, Kawaguchi, Naomasa, Fujita, Masaaki, Takada, Yoko K., Matsuura, Nariaki, Zhao, Min, Takada, Yoshikazu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585250/
https://ncbi.nlm.nih.gov/pubmed/23469107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057927
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