A Dominant-Negative FGF1 Mutant (the R50E Mutant) Suppresses Tumorigenesis and Angiogenesis

Fibroblast growth factor-1 (FGF1) and FGF2 play a critical role in angiogenesis, a formation of new blood vessels from existing blood vessels. Integrins are critically involved in FGF signaling through crosstalk. We previously reported that FGF1 directly binds to integrin αvβ3 and induces FGF recept...

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Detaylı Bibliyografya
Asıl Yazarlar: Mori, Seiji, Tran, Vu, Nishikawa, Kyoko, Kaneda, Teruya, Hamada, Yoshinosuke, Kawaguchi, Naomasa, Fujita, Masaaki, Takada, Yoko K., Matsuura, Nariaki, Zhao, Min, Takada, Yoshikazu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585250/
https://ncbi.nlm.nih.gov/pubmed/23469107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057927
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