The Chemokine Fractalkine Can Activate Integrins without CX3CR1 through Direct Binding to a Ligand-Binding Site Distinct from the Classical RGD-Binding Site

Ítems similars

• Integrins αvβ3 and α4β1 act as co-receptors for fractalkine and the integrin-binding defective mutant of fractalkine is an antagonist of CX3CR1
  per: Fujita, Masaaki, et al.
  Publicat: (2012)
• Stromal cell-derived factor-1 (CXCL12) activates integrins by direct binding to an allosteric ligand-binding site (site 2) of integrins without CXCR4.
  per: Fujita, Masaaki, et al.
  Publicat: (2018)
• Crosstalk between insulin-like growth factor (IGF) receptor and integrins through direct integrin binding to IGF1
  per: Takada, Yoshikazu, et al.
  Publicat: (2017)
• Fractalkine receptor chemokine (CX3CR1) influences on cervical and lumbar disc herniation
  per: Oh, In-Soo, et al.
  Publicat: (2015)
• Proinflammatory Secreted Phospholipase A2 Type IIA (sPLA-IIA) Induces Integrin Activation through Direct Binding to a Newly Identified Binding Site (Site 2) in Integrins αvβ3, α4β1, and α5β1
  per: Fujita, Masaaki, et al.
  Publicat: (2015)