Direct Binding of the EGF-like Domain of Neuregulin-1 to Integrins (αvβ3 and α6β4) Is Involved in Neuregulin-1/ErbB Signaling

Integrin-growth factor receptor cross-talk plays a role in growth factor signaling, but the specifics are unclear. In a current model, integrins and growth factor receptors independently bind to their ligands (extracellular matrix and growth factors, respectively). We discovered that neuregulin-1 (N...

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Hlavní autoři: Ieguchi, Katsuaki, Fujita, Masaaki, Ma, Zi, Davari, Parastoo, Taniguchi, Yukimasa, Sekiguchi, Kiyotoshi, Wang, Bobby, Takada, Yoko K., Takada, Yoshikazu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Glycobiology and Extracellular Matrices
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951213/
https://ncbi.nlm.nih.gov/pubmed/20682778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.113878
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