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Clozapine-dependent inhibition of EGF/neuregulin receptor (ErbB) kinases

Clozapine is an antipsychotic agent prescribed to psychotic patients exhibiting tolerance and/or resistance to the conventional antipsychotic medications that mainly drive monoamine antagonism. As the pharmacological fundamentals of its unique antipsychotic profile have been unrevealed, here, we att...

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Bibliografiske detaljer
Udgivet i:Transl Psychiatry
Main Authors: Kobayashi, Yutaro, Iwakura, Yuriko, Sotoyama, Hidekazu, Kitayama, Eiko, Takei, Nobuyuki, Someya, Toshiyuki, Nawa, Hiroyuki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675791/
https://ncbi.nlm.nih.gov/pubmed/31371697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-019-0519-1
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