Neuropathologic Implication of Peripheral Neuregulin-1 and EGF Signals in Dopaminergic Dysfunction and Behavioral Deficits Relevant to Schizophrenia: Their Target Cells and Time Window

Neuregulin-1 and epidermal growth factor (EGF) are implicated in the pathogenesis of schizophrenia. To test the developmental hypothesis for schizophrenia, we administered these factors to rodent pups, juveniles, and adults and characterized neurobiological and behavioral consequences. These factors...

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Detalhes bibliográficos
Main Authors: Nawa, Hiroyuki, Sotoyama, Hidekazu, Iwakura, Yuriko, Takei, Nobuyuki, Namba, Hisaaki
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052624/
https://ncbi.nlm.nih.gov/pubmed/24949465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/697935
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