Neuropathologic Implication of Peripheral Neuregulin-1 and EGF Signals in Dopaminergic Dysfunction and Behavioral Deficits Relevant to Schizophrenia: Their Target Cells and Time Window

Neuregulin-1 and epidermal growth factor (EGF) are implicated in the pathogenesis of schizophrenia. To test the developmental hypothesis for schizophrenia, we administered these factors to rodent pups, juveniles, and adults and characterized neurobiological and behavioral consequences. These factors...

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Bibliographische Detailangaben
Hauptverfasser: Nawa, Hiroyuki, Sotoyama, Hidekazu, Iwakura, Yuriko, Takei, Nobuyuki, Namba, Hisaaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2014
Schlagworte:
Review Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052624/
https://ncbi.nlm.nih.gov/pubmed/24949465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/697935
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