Mutations in the GABA(A) receptor that mimic the allosteric ligand, etomidate

Por Forman, Stuart A., Stewart, Deirdre
Publicado em 2012

The Two Etomidate Sites in α1β2γ2 GABA(A) Receptors Contribute Equally and Non-cooperatively to Modulation of Channel Gating

Por Guitchounts, Grigori, Stewart, Deirdre S., Forman, Stuart A.
Publicado em 2012

State-Dependent Etomidate Occupancy of Its Allosteric Agonist Sites Measured in a Cysteine-Substituted GABA(A) Receptor

Por Stewart, Deirdre S., Hotta, Mayo, Desai, Rooma, Forman, Stuart A.
Publicado em 2013

Multiple Transmembrane Binding Sites for p-Trifluoromethyldiazirinyl-etomidate, a Photoreactive Torpedo Nicotinic Acetylcholine Receptor Allosteric Inhibitor

Por Hamouda, Ayman K., Stewart, Deirdre S., Husain, S. Shaukat, Cohen, Jonathan B.
Publicado em 2011

Validation of the ApneaLink™ for the Screening of Sleep Apnea: a Novel and Simple Single-Channel Recording Device

Por Erman, Milton K., Stewart, Deirdre, Einhorn, Daniel, Gordon, Nancy, Casal, Eileen
Publicado em 2007

Tryptophan Mutations at Azi-Etomidate Photo-Incorporation Sites on α(1) or β(2) Subunits Enhance GABA(A) Receptor Gating and Reduce Etomidate Modulation

Por Stewart, Deirdre, Desai, Rooma, Cheng, Qi, Liu, Aiping, Forman, Stuart A.
Publicado em 2008

Mutations at Beta N265 in γ-Aminobutyric Acid Type A Receptors Alter Both Binding Affinity and Efficacy of Potent Anesthetics

Por Stewart, Deirdre S., Pierce, David W., Hotta, Mayo, Stern, Alex T., Forman, Stuart A.
Publicado em 2014

Identifying Barbiturate Binding Sites in a Nicotinic Acetylcholine Receptor with [(3)H]Allyl m-Trifluoromethyldiazirine Mephobarbital, a Photoreactive Barbiturate

Por Hamouda, Ayman K., Stewart, Deirdre S., Chiara, David C., Savechenkov, Pavel Y., Bruzik, Karol S., Cohen, Jonathan B.
Publicado em 2014

Tryptophan and Cysteine Mutations in M1 Helices of α1β3γ2L γ-Aminobutyric Acid Type A Receptors Indicate Distinct Inter-subunit Sites for Four Intravenous Anesthetics and One Orpha...

Por Nourmahnad, Anahita, Stern, Alex T, Hotta, Mayo, Stewart, Deirdre S., Ziemba, Alexis M., Szabo, Andrea, Forman, Stuart A.
Publicado no Anesthesiology (2016)

Desformylflustrabromine (dFBr) and [(3)H]dFBr-Labeled Binding Sites in a Nicotinic Acetylcholine Receptor

Por Hamouda, Ayman K., Wang, Ze-Jun, Stewart, Deirdre S., Jain, Atul D., Glennon, Richard A., Cohen, Jonathan B.
Publicado no Mol Pharmacol (2015)

Cysteine Substitutions Define Etomidate Binding and Gating Linkages in the α-M1 Domain of γ-Aminobutyric Acid Type A (GABA(A)) Receptors

Por Stewart, Deirdre S., Hotta, Mayo, Li, Guo-dong, Desai, Rooma, Chiara, David C., Olsen, Richard W., Forman, Stuart A.
Publicado em 2013

p-(4-Azipentyl)-propofol: A Potent Photoreactive General Anesthetic Derivative of Propofol

Por Stewart, Deirdre S., Savechenkov, Pavel Y., Dostalova, Zuzana, Chiara, David C., Ge, Rile, Raines, Douglas E., Cohne, Jonathan B., Forman, Stuart A., Bruzik, Karol S., Miller, Keith W.
Publicado em 2011

Allyl m-Trifluoromethyldiazirine Mephobarbital: An Unusually Potent Enantioselective and Photoreactive Barbiturate General Anesthetic

Por Savechenkov, Pavel Y., Zhang, Xi, Chiara, David C., Stewart, Deirdre S., Ge, Rile, Zhou, Xiaojuan, Raines, Douglas E., Cohen, Jonathan B., Forman, Stuart A., Miller, Keith W., Bruzik, Karol S.
Publicado em 2012

Carboetomidate: A Pyrrole Analogue of Etomidate Designed Not To Suppress Adrenocortical Function

Por Cotten, Joseph F., Forman, Stuart A., Laha, Joydev K., Cuny, Gregory D., Husain, S. Shaukat, Miller, Keith W., Nguyen, Hieu H., Kelly, Elizabeth W., Stewart, Deirdre, Liu, Aiping, Raines, Douglas E.
Publicado em 2010

p-Trifluoromethyldiazirinyl-etomidate: a potent photoreactive general anesthetic derivative of etomidate that is selective for ligand-gated cationic ion channels

Por Husain, S. Shaukat, Stewart, Deirdre, Desai, Rooma, Hamouda, Ayman K., Li, S. Guo-Dong, Kelly, Elizabeth, Dostalova, Zuzana, Zhou, Xiaojuan, Cotten, Joseph F., Raines, Douglas A., Olsen, Richard W., Cohen, Jonathan B., Forman, Stuart A., Miller, Keith W.
Publicado em 2010