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Desformylflustrabromine (dFBr) and [(3)H]dFBr-Labeled Binding Sites in a Nicotinic Acetylcholine Receptor
Desformylflustrabromine (dFBr) is a positive allosteric modulator (PAM) of α4β2 and α2β2 nAChRs that, at concentrations >1 µM, also inhibits these receptors and α7 nAChRs. However, its interactions with muscle-type nAChRs have not been characterized, and the locations of its binding site(s) in an...
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| Wydane w: | Mol Pharmacol |
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| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4468644/ https://ncbi.nlm.nih.gov/pubmed/25870334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.098913 |
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