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Identifying Barbiturate Binding Sites in a Nicotinic Acetylcholine Receptor with [(3)H]Allyl m-Trifluoromethyldiazirine Mephobarbital, a Photoreactive Barbiturate

At concentrations that produce anesthesia, many barbituric acid derivatives act as positive allosteric modulators of inhibitory GABA(A) receptors (GABA(A)Rs) and inhibitors of excitatory nicotinic acetylcholine receptors (nAChRs). Recent research on [(3)H]R-mTFD-MPAB ([(3)H]R-5-allyl-1-methyl-5-(m-t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Hamouda, Ayman K., Stewart, Deirdre S., Chiara, David C., Savechenkov, Pavel Y., Bruzik, Karol S., Cohen, Jonathan B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Pharmacology and Experimental Therapeutics 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990015/
https://ncbi.nlm.nih.gov/pubmed/24563544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.090985
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