Modifying Methoxycarbonyl Etomidate’s Inter-Ester Spacer Optimizes In Vitro Metabolic Stability and In Vivo Hypnotic Potency and Duration of Action

Por Husain, S. Shaukat, Pejo, Ervin, Ge, Rile, Raines, Douglas E.
Publicado em 2012

Adrenocortical suppression and recovery after continuous hypnotic infusion: etomidate versus its soft analogue cyclopropyl-methoxycarbonyl metomidate

Por Ge, Rile, Pejo, Ervin, Cotten, Joseph F, Raines, Douglas E
Publicado em 2013

Electroencephalographic and Hypnotic Recoveries Following Brief and Prolonged Infusions of Etomidate and Optimized Soft Etomidate Analogs

Por Ge, Rile, Pejo, Ervin, Husain, S. Shaukat, Cotten, Joseph F., Raines, Douglas E.
Publicado em 2012

Electroencephalographic Recovery, Hypnotic Emergence, and the Effects of Metabolite Following Continuous Infusions of a Rapidly Metabolized Etomidate Analog in Rats

Por Pejo, Ervin, Ge, Rile, Banacos, Natalie, Cotten, Joseph F., Husain, S. Shaukat, Raines, Douglas E.
Publicado em 2012

Carboetomidate: An Analog of Etomidate That Interacts Weakly with 11β-Hydroxylase

Por Shanmugasundararaj, Sivananthaperumal, Zhou, Xiaojuan, Neunzig, Jens, Bernhardt, Rita, Cotten, Joseph F., Ge, Rile, Miller, Keith W., Raines, Douglas E.
Publicado em 2013

p-(4-Azipentyl)-propofol: A Potent Photoreactive General Anesthetic Derivative of Propofol

Por Stewart, Deirdre S., Savechenkov, Pavel Y., Dostalova, Zuzana, Chiara, David C., Ge, Rile, Raines, Douglas E., Cohne, Jonathan B., Forman, Stuart A., Bruzik, Karol S., Miller, Keith W.
Publicado em 2011

Allyl m-Trifluoromethyldiazirine Mephobarbital: An Unusually Potent Enantioselective and Photoreactive Barbiturate General Anesthetic

Por Savechenkov, Pavel Y., Zhang, Xi, Chiara, David C., Stewart, Deirdre S., Ge, Rile, Zhou, Xiaojuan, Raines, Douglas E., Cohen, Jonathan B., Forman, Stuart A., Miller, Keith W., Bruzik, Karol S.
Publicado em 2012