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Carboetomidate: An Analog of Etomidate That Interacts Weakly with 11β-Hydroxylase
BACKGROUND: Carboetomidate is a pyrrole etomidate analog that is 3 orders of magnitude less potent an inhibitor of in vitro cortisol synthesis than etomidate and does not inhibit in vivo steroid production. Although carboetomidate's reduced functional effect on steroid synthesis is thought to r...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836822/ https://ncbi.nlm.nih.gov/pubmed/23492967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e31828b3637 |
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