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The Pyrrole Etomidate Analog Carboetomidate Potently Inhibits Human 5-HT(3A) Receptor Function: Comparisons with Etomidate and Potential Implications for Emetogenesis
BACKGROUND: 5-Hydroxytryptamine type 3 (5-HT(3)) receptors are excitatory ion channels belonging to the cys-loop family of ligand-gated ion channels. They are involved in nausea and vomiting and their antagonists are used clinically as antiemeticdrugs. We previously reported the development of a nov...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3582768/ https://ncbi.nlm.nih.gov/pubmed/23400978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e31827d204d |
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