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The Pyrrole Etomidate Analog Carboetomidate Potently Inhibits Human 5-HT(3A) Receptor Function: Comparisons with Etomidate and Potential Implications for Emetogenesis

BACKGROUND: 5-Hydroxytryptamine type 3 (5-HT(3)) receptors are excitatory ion channels belonging to the cys-loop family of ligand-gated ion channels. They are involved in nausea and vomiting and their antagonists are used clinically as antiemeticdrugs. We previously reported the development of a nov...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Desai, Rooma, Miller, Keith W., Raines, Douglas E.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582768/
https://ncbi.nlm.nih.gov/pubmed/23400978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e31827d204d
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