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Electroencephalographic and Hypnotic Recoveries Following Brief and Prolonged Infusions of Etomidate and Optimized Soft Etomidate Analogs

BACKGROUND: Methoxycarbonyl etomidate is the prototypical soft etomidate analog. Because it has relatively low potency and is extremely rapidly metabolized, large quantities must be infused to maintain hypnosis. Consequently with prolonged infusion, metabolite reaches sufficient concentrations to de...

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Detalhes bibliográficos
Main Authors: Ge, Rile, Pejo, Ervin, Husain, S. Shaukat, Cotten, Joseph F., Raines, Douglas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509380/
https://ncbi.nlm.nih.gov/pubmed/22929726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31826d3de2
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