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Distinct Hypnotic Recoveries After Infusions of Methoxycarbonyl Etomidate and Cyclopropyl Methoxycarbonyl Metomidate: The Role of the Metabolite

BACKGROUND: Methoxycarbonyl etomidate (MOC-etomidate) and cyclopropyl methoxycarbonyl metomidate (CPMM) are rapidly metabolized “soft” etomidate analogues. CPMM’s duration of hypnotic effect is context-insensitive whereas MOC-etomidate’s is not. In the current study, we tested the hypothesis that CP...

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Publicado en:Anesth Analg
Main Authors: Pejo, Ervin, Liu, Jifeng, Lin, Xiangjie, Raines, Douglas E.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800831/
https://ncbi.nlm.nih.gov/pubmed/26991617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000001146
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