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Pharmacological Studies of Methoxycarbonyl Etomidate's Carboxylic Acid Metabolite

BACKGROUND: Methoxycarbonyl etomidate (MOC-etomidate) is a rapidly metabolized and ultra-short acting etomidate analog that does not produce prolonged adrenocortical suppression after bolus administration. Its metabolite (MOC-ECA) is a carboxylic acid whose pharmacology is undefined. We hypothesized...

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Detalhes bibliográficos
Main Authors: Ge, Ri Le, Pejo, Ervin, Haburcak, Marian, Husain, S. Shaukat, Forman, Stuart A., Raines, Douglas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291806/
https://ncbi.nlm.nih.gov/pubmed/22052979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e318239c6ca
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