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Adrenocortical suppression and recovery after continuous hypnotic infusion: etomidate versus its soft analogue cyclopropyl-methoxycarbonyl metomidate

INTRODUCTION: Etomidate is no longer administered as a continuous infusion for anesthetic maintenance or sedation, because it results in profound and persistent suppression of adrenocortical steroid synthesis with potentially lethal consequences in critically ill patients. We hypothesized that rapid...

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Detalhes bibliográficos
Main Authors: Ge, Rile, Pejo, Ervin, Cotten, Joseph F, Raines, Douglas E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057162/
https://ncbi.nlm.nih.gov/pubmed/23363638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc12494
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