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Mutations in the GABA(A) receptor that mimic the allosteric ligand, etomidate
Etomidate is a hydrophobic molecule, a potent general anesthetic, and the best understood drug in this group. Etomidate’s target molecules are GABA(A) receptors, its site of action has been identified with photolabeling, and a quantitative allosteric co-agonist model has emerged for etomidate effect...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3360466/ https://ncbi.nlm.nih.gov/pubmed/22052498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-334-9_17 |
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