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Mutations in the GABA(A) receptor that mimic the allosteric ligand, etomidate

Etomidate is a hydrophobic molecule, a potent general anesthetic, and the best understood drug in this group. Etomidate’s target molecules are GABA(A) receptors, its site of action has been identified with photolabeling, and a quantitative allosteric co-agonist model has emerged for etomidate effect...

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Detalhes bibliográficos
Main Authors: Forman, Stuart A., Stewart, Deirdre
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360466/
https://ncbi.nlm.nih.gov/pubmed/22052498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-334-9_17
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