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Monod-Wyman-Changeux Allosteric Mechanisms of Action and the Pharmacology of Etomidate

PURPOSE OF REVIEW: Formal Monod-Wyman-Changeux allosteric mechanisms have proven valuable in framing research on the mechanism of etomidate action on its major molecular targets, GABA(A) receptors. However, the mathematical formalism of these mechanisms makes them difficult to comprehend. RECENT FIN...

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Detalhes bibliográficos
Autor principal: Forman, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673006/
https://ncbi.nlm.nih.gov/pubmed/22614249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ACO.0b013e328354feea
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