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An analytic solution to the Monod-Wyman-Changeux model and all parameters in this model.

Starting from the Monod-Wyman-Changeux (MWC) model (Monod, J., J. Wyman, and J. P. Changeux. 1965. J. Mol. Biol. 12:88-118), we obtain an analytical expression for the slope of the Hill plot at any ligand concentration. Furthermore, we derive an equation satisfied by the ligand concentration at the...

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Bibliographic Details
Main Authors: Zhou, G, Ho, P S, van Holde, K E
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1330468/
https://ncbi.nlm.nih.gov/pubmed/2713440
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