Llwytho...
Cysteine Substitutions Define Etomidate Binding and Gating Linkages in the α-M1 Domain of γ-Aminobutyric Acid Type A (GABA(A)) Receptors
Etomidate is a potent general anesthetic that acts as an allosteric co-agonist at GABA(A) receptors. Photoreactive etomidate derivatives labeled αMet-236 in transmembrane domain M1, which structural models locate in the β+/α- subunit interface. Other nearby residues may also contribute to etomidate...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Society for Biochemistry and Molecular Biology
2013
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798502/ https://ncbi.nlm.nih.gov/pubmed/24009076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.494583 |
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