Functional Dissection of Eyes absent Reveals New Modes of Regulation within the Retinal Determination Gene Network

по Silver, Serena J., Davies, Erin L., Doyon, Laura, Rebay, Ilaria
Опубликовано 2003

Functional screening identifies miR-315 as a potent activator of Wingless signaling

по Silver, Serena J., Hagen, Joshua W., Okamura, Katsutomo, Perrimon, Norbert, Lai, Eric C.
Опубликовано 2007

Using Drosophila to Decipher How Mutations Associated With Human Branchio-Oto-Renal Syndrome and Optical Defects Compromise the Protein Tyrosine Phosphatase and Transcriptional Fun...

по Mutsuddi, Mousumi, Chaffee, Benjamin, Cassidy, Justin, Silver, Serena J., Tootle, Tina L., Rebay, Ilaria
Опубликовано 2005

Generation of High-Throughput Three-Dimensional Tumor Spheroids for Drug Screening

по Griner, Lesley Mathews, Gampa, Kalyani, Do, Toan, Nguyen, Huyen, Farley, David, Hogan, Christopher J., Auld, Douglas S., Silver, Serena J.
Опубликовано в: J Vis Exp (2018)

Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning

по Jones, Thouis R., Carpenter, Anne E., Lamprecht, Michael R., Moffat, Jason, Silver, Serena J., Grenier, Jennifer K., Castoreno, Adam B., Eggert, Ulrike S., Root, David E., Golland, Polina, Sabatini, David M.
Опубликовано 2009

CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity

по Kim, So Young, Dunn, Ian F., Firestein, Ron, Gupta, Piyush, Wardwell, Leslie, Repich, Kara, Schinzel, Anna C., Wittner, Ben, Silver, Serena J., Root, David E., Boehm, Jesse S., Ramaswamy, Sridhar, Lander, Eric S., Hahn, William C.
Опубликовано 2010

A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection

по Shapira, Sagi D., Gat-Viks, Irit, Shum, Bennett O.V., Dricot, Amelie, Degrace, Marciela M., Liguo, Wu, Gupta, Piyush B., Hao, Tong, Silver, Serena J., Root, David E., Hill, David E., Regev, Aviv, Hacohen, Nir
Опубликовано 2009

Proteomic and Genetic Approaches Identify Syk as an AML Target

по Hahn, Cynthia K., Berchuck, Jacob E., Ross, Kenneth N., Kakoza, Rose M., Clauser, Karl, Schinzel, Anna C., Ross, Linda, Galinsky, Ilene, Davis, Tina N., Silver, Serena J., Root, David E., Stone, Richard M., DeAngelo, Daniel J., Carroll, Martin, Hahn, William C., Carr, Steven A., Golub, Todd R., Kung, Andrew L., Stegmaier, Kimberly
Опубликовано 2009

CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

по Firestein, Ron, Bass, Adam J., Kim, So Young, Dunn, Ian F., Silver, Serena J., Guney, Isil, Freed, Ellen, Ligon, Azra H., Vena, Natalie, Ogino, Shuji, Chheda, Milan G., Tamayo, Pablo, Finn, Stephen, Shrestha, Yashaswi, Boehm, Jesse S., Jain, Supriya, Bojarski, Emeric, Mermel, Craig, Barretina, Jordi, Chan, Jennifer A., Baselga, Jose, Tabernero, Josep, Root, David E., Fuchs, Charles S., Loda, Massimo, Shivdasani, Ramesh A., Meyerson, Matthew, Hahn, William C.
Опубликовано 2008

An epigenetic mechanism of resistance to targeted therapy in T-cell acute lymphoblastic leukemia

по Knoechel, Birgit, Roderick, Justine E., Williamson, Kaylyn E., Zhu, Jiang, Lohr, Jens G., Cotton, Matthew J., Gillespie, Shawn M., Fernandez, Daniel, Ku, Manching, Wang, Hongfang, Piccioni, Federica, Silver, Serena J., Jain, Mohit, Pearson, Daniel, Kluk, Michael J., Ott, Christopher J., Shultz, Leonard D., Brehm, Michael A., Greiner, Dale L., Gutierrez, Alejandro, Stegmaier, Kimberly, Kung, Andrew L., Root, David E., Bradner, James E., Aster, Jon C., Kelliher, Michelle A., Bernstein, Bradley E.
Опубликовано 2014

The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(–) stem cell–like breast cancer cells in human tumors

по Marotta, Lauren L.C., Almendro, Vanessa, Marusyk, Andriy, Shipitsin, Michail, Schemme, Janina, Walker, Sarah R., Bloushtain-Qimron, Noga, Kim, Jessica J., Choudhury, Sibgat A., Maruyama, Reo, Wu, Zhenhua, Gönen, Mithat, Mulvey, Laura A., Bessarabova, Marina O., Huh, Sung Jin, Silver, Serena J., Kim, So Young, Park, So Yeon, Lee, Hee Eun, Anderson, Karen S., Richardson, Andrea L., Nikolskaya, Tatiana, Nikolsky, Yuri, Liu, X. Shirley, Root, David E., Hahn, William C., Frank, David A., Polyak, Kornelia
Опубликовано 2011

ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor initiating cell state

по Chudnovsky, Yakov, Kim, Dohoon, Zheng, Siyuan, Whyte, Warren A., Bansal, Mukesh, Bray, Mark-Anthony, Gopal, Shuba, Theisen, Matthew A., Bilodeau, Steve, Thiru, Prathapan, Muffat, Julien, Yilmaz, Omer H., Mitalipova, Maya, Woolard, Kevin, Lee, Jeongwu, Nishimura, Riko, Sakata, Nobuo, Fine, Howard A., Carpenter, Anne E., Silver, Serena J., Verhaak, Roel G. W., Califano, Andrea, Young, Richard A., Ligon, Keith L., Mellinghoff, Ingo K., Root, David E., Sabatini, David M., Hahn, William C., Chheda, Milan G.
Опубликовано 2014

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

по Barbie, David A., Tamayo, Pablo, Boehm, Jesse S., Kim, So Young, Moody, Susan E., Dunn, Ian F., Schinzel, Anna C., Sandy, Peter, Meylan, Etienne, Scholl, Claudia, Fröhling, Stefan, Chan, Edmond M., Sos, Martin L., Michel, Kathrin, Mermel, Craig, Silver, Serena J., Weir, Barbara A., Reiling, Jan H., Sheng, Qing, Gupta, Piyush B., Wadlow, Raymond C., Le, Hanh, Hoersch, Sebastian, Wittner, Ben S., Ramaswamy, Sridhar, Livingston, David M., Sabatini, David M., Meyerson, Matthew, Thomas, Roman K., Lander, Eric S., Mesirov, Jill P., Root, David E., Gilliland, D. Gary, Jacks, Tyler, Hahn, William C.
Опубликовано 2009

Integrative screening approach identifies regulators of polyploidization and targets for acute megakaryocytic leukemia

по Wen, Qiang, Goldenson, Benjamin, Silver, Serena J., Schenone, Monica, Dancik, Vladimir, Huang, Zan, Wang, Ling-Zhi, Lewis, Timothy, An, W. Frank, Li, Xiaoyu, Bray, Mark-Anthony, Thiollier, Clarisse, Diebold, Lauren, Gilles, Laure, Vokes, Martha S., Moore, Christopher B., Bliss-Moreau, Meghan, VerPlank, Lynn, Tolliday, Nicola J., Mishra, Rama, Vemula, Sasidhar, Shi, Jianjian, Wei, Lei, Kapur, Reuben, Lopez, Cécile K., Gerby, Bastien, Ballerini, Paola, Pflumio, Francoise, Gilliland, D. Gary, Goldberg, Liat, Birger, Yehudit, Izraeli, Shai, Gamis, Alan S., Smith, Franklin O., Woods, William G., Taub, Jeffrey, Scherer, Christina A., Bradner, James, Goh, Boon-Cher, Mercher, Thomas, Carpenter, Anne E., Gould, Robert J., Clemons, Paul A., Carr, Steven A., Root, David E., Schreiber, Stuart L., Stern, Andrew M., Crispino, John D.
Опубликовано 2012