Functional Dissection of Eyes absent Reveals New Modes of Regulation within the Retinal Determination Gene Network

door Silver, Serena J., Davies, Erin L., Doyon, Laura, Rebay, Ilaria
Gepubliceerd in 2003

Functional screening identifies miR-315 as a potent activator of Wingless signaling

door Silver, Serena J., Hagen, Joshua W., Okamura, Katsutomo, Perrimon, Norbert, Lai, Eric C.
Gepubliceerd in 2007

Using Drosophila to Decipher How Mutations Associated With Human Branchio-Oto-Renal Syndrome and Optical Defects Compromise the Protein Tyrosine Phosphatase and Transcriptional Fun...

door Mutsuddi, Mousumi, Chaffee, Benjamin, Cassidy, Justin, Silver, Serena J., Tootle, Tina L., Rebay, Ilaria
Gepubliceerd in 2005

Generation of High-Throughput Three-Dimensional Tumor Spheroids for Drug Screening

door Griner, Lesley Mathews, Gampa, Kalyani, Do, Toan, Nguyen, Huyen, Farley, David, Hogan, Christopher J., Auld, Douglas S., Silver, Serena J.
Gepubliceerd in J Vis Exp (2018)

Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning

door Jones, Thouis R., Carpenter, Anne E., Lamprecht, Michael R., Moffat, Jason, Silver, Serena J., Grenier, Jennifer K., Castoreno, Adam B., Eggert, Ulrike S., Root, David E., Golland, Polina, Sabatini, David M.
Gepubliceerd in 2009

CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity

door Kim, So Young, Dunn, Ian F., Firestein, Ron, Gupta, Piyush, Wardwell, Leslie, Repich, Kara, Schinzel, Anna C., Wittner, Ben, Silver, Serena J., Root, David E., Boehm, Jesse S., Ramaswamy, Sridhar, Lander, Eric S., Hahn, William C.
Gepubliceerd in 2010

A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection

door Shapira, Sagi D., Gat-Viks, Irit, Shum, Bennett O.V., Dricot, Amelie, Degrace, Marciela M., Liguo, Wu, Gupta, Piyush B., Hao, Tong, Silver, Serena J., Root, David E., Hill, David E., Regev, Aviv, Hacohen, Nir
Gepubliceerd in 2009

Proteomic and Genetic Approaches Identify Syk as an AML Target

door Hahn, Cynthia K., Berchuck, Jacob E., Ross, Kenneth N., Kakoza, Rose M., Clauser, Karl, Schinzel, Anna C., Ross, Linda, Galinsky, Ilene, Davis, Tina N., Silver, Serena J., Root, David E., Stone, Richard M., DeAngelo, Daniel J., Carroll, Martin, Hahn, William C., Carr, Steven A., Golub, Todd R., Kung, Andrew L., Stegmaier, Kimberly
Gepubliceerd in 2009

CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

door Firestein, Ron, Bass, Adam J., Kim, So Young, Dunn, Ian F., Silver, Serena J., Guney, Isil, Freed, Ellen, Ligon, Azra H., Vena, Natalie, Ogino, Shuji, Chheda, Milan G., Tamayo, Pablo, Finn, Stephen, Shrestha, Yashaswi, Boehm, Jesse S., Jain, Supriya, Bojarski, Emeric, Mermel, Craig, Barretina, Jordi, Chan, Jennifer A., Baselga, Jose, Tabernero, Josep, Root, David E., Fuchs, Charles S., Loda, Massimo, Shivdasani, Ramesh A., Meyerson, Matthew, Hahn, William C.
Gepubliceerd in 2008

An epigenetic mechanism of resistance to targeted therapy in T-cell acute lymphoblastic leukemia

door Knoechel, Birgit, Roderick, Justine E., Williamson, Kaylyn E., Zhu, Jiang, Lohr, Jens G., Cotton, Matthew J., Gillespie, Shawn M., Fernandez, Daniel, Ku, Manching, Wang, Hongfang, Piccioni, Federica, Silver, Serena J., Jain, Mohit, Pearson, Daniel, Kluk, Michael J., Ott, Christopher J., Shultz, Leonard D., Brehm, Michael A., Greiner, Dale L., Gutierrez, Alejandro, Stegmaier, Kimberly, Kung, Andrew L., Root, David E., Bradner, James E., Aster, Jon C., Kelliher, Michelle A., Bernstein, Bradley E.
Gepubliceerd in 2014

The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(–) stem cell–like breast cancer cells in human tumors

door Marotta, Lauren L.C., Almendro, Vanessa, Marusyk, Andriy, Shipitsin, Michail, Schemme, Janina, Walker, Sarah R., Bloushtain-Qimron, Noga, Kim, Jessica J., Choudhury, Sibgat A., Maruyama, Reo, Wu, Zhenhua, Gönen, Mithat, Mulvey, Laura A., Bessarabova, Marina O., Huh, Sung Jin, Silver, Serena J., Kim, So Young, Park, So Yeon, Lee, Hee Eun, Anderson, Karen S., Richardson, Andrea L., Nikolskaya, Tatiana, Nikolsky, Yuri, Liu, X. Shirley, Root, David E., Hahn, William C., Frank, David A., Polyak, Kornelia
Gepubliceerd in 2011

ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor initiating cell state

door Chudnovsky, Yakov, Kim, Dohoon, Zheng, Siyuan, Whyte, Warren A., Bansal, Mukesh, Bray, Mark-Anthony, Gopal, Shuba, Theisen, Matthew A., Bilodeau, Steve, Thiru, Prathapan, Muffat, Julien, Yilmaz, Omer H., Mitalipova, Maya, Woolard, Kevin, Lee, Jeongwu, Nishimura, Riko, Sakata, Nobuo, Fine, Howard A., Carpenter, Anne E., Silver, Serena J., Verhaak, Roel G. W., Califano, Andrea, Young, Richard A., Ligon, Keith L., Mellinghoff, Ingo K., Root, David E., Sabatini, David M., Hahn, William C., Chheda, Milan G.
Gepubliceerd in 2014

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

door Barbie, David A., Tamayo, Pablo, Boehm, Jesse S., Kim, So Young, Moody, Susan E., Dunn, Ian F., Schinzel, Anna C., Sandy, Peter, Meylan, Etienne, Scholl, Claudia, Fröhling, Stefan, Chan, Edmond M., Sos, Martin L., Michel, Kathrin, Mermel, Craig, Silver, Serena J., Weir, Barbara A., Reiling, Jan H., Sheng, Qing, Gupta, Piyush B., Wadlow, Raymond C., Le, Hanh, Hoersch, Sebastian, Wittner, Ben S., Ramaswamy, Sridhar, Livingston, David M., Sabatini, David M., Meyerson, Matthew, Thomas, Roman K., Lander, Eric S., Mesirov, Jill P., Root, David E., Gilliland, D. Gary, Jacks, Tyler, Hahn, William C.
Gepubliceerd in 2009

Integrative screening approach identifies regulators of polyploidization and targets for acute megakaryocytic leukemia

door Wen, Qiang, Goldenson, Benjamin, Silver, Serena J., Schenone, Monica, Dancik, Vladimir, Huang, Zan, Wang, Ling-Zhi, Lewis, Timothy, An, W. Frank, Li, Xiaoyu, Bray, Mark-Anthony, Thiollier, Clarisse, Diebold, Lauren, Gilles, Laure, Vokes, Martha S., Moore, Christopher B., Bliss-Moreau, Meghan, VerPlank, Lynn, Tolliday, Nicola J., Mishra, Rama, Vemula, Sasidhar, Shi, Jianjian, Wei, Lei, Kapur, Reuben, Lopez, Cécile K., Gerby, Bastien, Ballerini, Paola, Pflumio, Francoise, Gilliland, D. Gary, Goldberg, Liat, Birger, Yehudit, Izraeli, Shai, Gamis, Alan S., Smith, Franklin O., Woods, William G., Taub, Jeffrey, Scherer, Christina A., Bradner, James, Goh, Boon-Cher, Mercher, Thomas, Carpenter, Anne E., Gould, Robert J., Clemons, Paul A., Carr, Steven A., Root, David E., Schreiber, Stuart L., Stern, Andrew M., Crispino, John D.
Gepubliceerd in 2012